Evicenter
P&T meetings

Zanzalintinib

Metastatic colorectal cancer

Also known as XL092
Manufacturer
Exelixis
Regulatory submission
NDA submitted December 2025
Launch
Not announced
65 sources

Section 5 of 6

Economic information and modeling report

1 evidence topic · 2 sources

Modeling overview

Summary

The economic evidence in this report concerns the disease and comparator treatment pathways. A systematic review reported average metastatic colorectal cancer treatment costs ranging from $12,346 to $293,461 across heterogeneous studies. A separate analysis of 82 participants used a US Medicare payer perspective and reported an incremental cost-effectiveness ratio of US$518,000 per quality-adjusted life-year gained. These figures do not estimate the acquisition cost, cost effectiveness, or budget impact of zanzalintinib.

Zanzalintinib-specific health technology assessment

No evidence found.

Zanzalintinib-specific acquisition price, annual treatment cost, price corridor, cost-effectiveness analysis, and budget-impact results

No evidence found.

Public zanzalintinib-specific economic model

No evidence found.

Budget impact model

Approach and framework

No evidence found.

Perspective and time frame

No evidence found.

Epidemiology and eligible population inputs

No evidence found.

Cost assumptions

No evidence found.

Model outcomes

No evidence found.

Results

Base case

No evidence found.

Scenario analyses

No evidence found.

Budget impact model discussion

No evidence found.