Product information and disease descriptionPlace of product in therapyDisease descriptionEpidemiology
Prevalence of Adenoid cystic carcinoma with solid histology or high-grade transformation
3 evidence topics · 4 sources
Summary: prevalence of ACC and of the aggressive subgroup
No published source reports the prevalence of ACC with solid histology or high-grade transformation. For ACC overall, Servier reports that more than 200,000 people have ACC worldwide. For all salivary gland cancers, the estimated global 1-year prevalence is about 42,000 cases (GLOBOCAN 2022). A 2020 ASCO abstract on the epidemiology of ACC in the United States could not be retrieved for quotation. Because survival in aggressive ACC is shorter than in ACC-II (median overall survival 3.44 versus 23.2 years in a proteogenomic cohort of 54 participants), the aggressive subgroup is expected to represent a smaller share of prevalent cases than of incident cases.