Burden of Hereditary angioedema
1 evidence topic · 3 sources
Summary
Hereditary angioedema is estimated to affect 1 in 50,000 people worldwide. Symptoms commonly begin in childhood and worsen during puberty. Intestinal attacks cause abdominal symptoms, and airway swelling can be life-threatening. A systematic review reported mean or median diagnostic delays ranging from 3.9 to 26 years. A multinational adult survey reported a mean of 11.5 attacks during the preceding six months, with a standard deviation of 14.2. These findings describe different populations and should not be treated as estimates from one cohort.