Ulixacaltamide

A population estimate placed US essential tremor prevalence at approximately 7.01 million people in 2012, whereas a separate analysis estimated 1.1 million US adults with diagnosed essential tremor in 2024. These estimates use different ascertainment approaches and do not establish a temporal decline. Reported burdens include impaired daily activities, depression, anxiety, falls, sleep disturbance, and caregiver assistance. One claims analysis reported annual all-cause healthcare costs of $17,560 per person with essential tremor in 2019 US dollars, including $2,233 attributed to essential tremor. In a clinic-based cohort, approximately 25% required care partners, with reported caregiving averaging 24 to 44 hours weekly.