Product information and disease description Place of product in therapy Disease description Epidemiology

Prevalence of Focal onset seizures

8 evidence topics · 8 sources

United States prevalence of active epilepsy, 2015

“In 2015, 1.2% of the U.S. population (3.4 million persons: 3 million adults and 470,000 children) reported active epilepsy (self-reported doctor-diagnosed epilepsy and under treatment or with recent seizures within 12 months of interview) or current epilepsy (parent-reported doctor-diagnosed epilepsy and current epilepsy).” (opens the source at this quote in a new tab)

United States prevalence of active epilepsy among adults, 2021

“In 2021, 1.1% of U.S. adults, (approximately 2,865,000 adults) reported active epilepsy” (opens the source at this quote in a new tab)

Current national estimates of active epilepsy

“CDC estimates that about 2.9 million U.S. adults had active epilepsy” (opens the source at this quote in a new tab)
“An estimated 456,000 U.S. children 17 or younger had active epilepsy in 2022” (opens the source at this quote in a new tab)

Treated prevalence of epilepsy and seizures in the United States, 2010 to 2018

“Treated prevalence was .38% (95% confidence interval [CI] = .34–.41) for epilepsy, .76% (95% CI = .71–.81) for seizure, and 1.14% (95% CI = 1.08–1.20) for epilepsy or seizure.” (opens the source at this quote in a new tab)

Global prevalence of active epilepsy

“In 2016, there were 45·9 million (95% UI 39·9–54·6) patients with all-active epilepsy (both idiopathic and secondary epilepsy globally; age-standardised prevalence 621·5 per 100 000 population; 540·1–737·0).” (opens the source at this quote in a new tab)
“Prevalence of active epilepsy increased with age, with peaks at 5–9 years (374·8 [280·1–490·0]) and at older than 80 years of age (545·1 [444·2–652·0]).” (opens the source at this quote in a new tab)

Proportion of prevalent epilepsy that is focal

“The prevalence of focal epilepsy was 3.70 per 1000, accounting for 61% of epilepsy” (opens the source at this quote in a new tab)
“Overall, estimates in 2016 for France, Germany, Italy, Spain, and the UK show that two-thirds of people with epilepsy had focal seizures, equating to over 1.3 million people” (opens the source at this quote in a new tab)

Proportion of people with epilepsy who are drug resistant

“approximately 40% of people with epilepsy are drug-resistant, further increasing the risks associated with epilepsy” (opens the source at this quote in a new tab)

Persistent seizures among United States adults with focal epilepsy

“The proportion of patients with persistent seizures (>1 per year) among AED users was higher in the U.S. (66.4%) than the 5EU (53.0%) and Brazil + 5EU (52.3%) datasets” (opens the source at this quote in a new tab)