Lupus nephritis retransplantation case report
8 evidence topics · 1 source
Objective
Immunoglobulin monitoring
Location and study date
No evidence found.
Study design
Eligibility criteria
Not applicable.
Treatment
Treatment before retransplantation
Study outcomes
Rationale for using donor-specific antibody reduction as the primary endpoint
Not applicable.
Statistical analysis description
Number of participants (Planned and analyzed)
Description of analysis sets
Not applicable.
Results
Participant disposition
No evidence found.
Baseline characteristics
Baseline features
| Characteristic | Quoted record |
|---|---|
| Underlying kidney disease | “lupus nephritis” |
| Sensitization | “cPRA>99 %” |
Efficacy results
Maximum reported total IgG depletion at 36 hours
| Outcome | Quoted value |
|---|---|
| Total IgG reduction from baseline | “-75 %” |
Health-related quality of life and patient-reported outcomes
No evidence found.
Safety results
No evidence found.
Study limitations
Summary
The report concerns one 51-year-old woman with lupus nephritis undergoing retransplantation. The absence of donor-specific antibody rebound at six months is an individual observation, not an estimate of response probability. The case does not establish comparative efficacy or safety in other highly sensitized transplant candidates.