Name: Lytenava (bevacizumab-vikg) in Neovascular age-related macular degeneration: Care management intervention strategies
Published: 2026-09-28T12:24:10-04:00

Product information and disease description Place of product in therapy Approaches to treatment

Care management intervention strategies

4 evidence topics · 4 sources

Treat-and-extend regimens

“requires repeated and frequent intravitreal injections of the drug, which are necessary to maintain the therapeutic effect, frequent clinical visits to monitor efficacy and safety, and a significant financial burden associated with high drug costs” (opens the source at this quote in a new tab)
“monthly, monthly for the first three months followed by PRN, every eight weeks, quarterly cross‐over from monthly to PRN, and treat‐and‐extend protocols” (opens the source at this quote in a new tab)

Home optical coherence tomography as a safety net between visits

“Home-based optical coherence tomography (OCT) has emerged as a potential tool to bridge this surveillance gap by enabling frequent, patient-administered imaging between office visits” (opens the source at this quote in a new tab)
“Persistent or recurring fluid was identified in 121 (65%) intervals, on average 32 days prior to the next office visit.” (opens the source at this quote in a new tab)
“Home OCT monitoring provides adjunctive information to support early detection of fluid and may facilitate timely clinical evaluation.” (opens the source at this quote in a new tab)

Amsler grid self-monitoring between visits

“Its portability and ease of use enable patients to participate actively in the management of their ocular health, allowing earlier detection of disease progression and more timely medical intervention.” (opens the source at this quote in a new tab)

Extended-interval dosing to reduce visit burden

“At week 48, after 4 initial monthly doses in the VABYSMO arm, 45% of patients received the Weeks 28 and 44 dosing, 33% of patients received the Weeks 24, 36 and 48 dosing, and the remaining 22% of patients received dosing every 8 weeks.” (opens the source at this quote in a new tab)