Name: SKY-0515 in Huntington's disease: Approach and framework
Published: 2026-09-16T18:00:43-04:00

Economic information and modeling report Budget impact model

Approach and framework

2 evidence topics · 2 sources

Budget impact analysis: eligible population and intervention mix (ISPOR task force)

“The eligible population is open in the sense that individuals enter or leave depending on whether they meet the criteria for inclusion (e.g., by developing the indication, meeting the restrictions, no longer having symptoms, and dying).” (opens the source at this quote in a new tab)
“A BIA compares scenarios defined by sets of, rather than specific individual, interventions. The starting scenario should be the current intervention mix for the eligible population. The current mix may include no intervention as well as interventions that might be replaced by the new one.” (opens the source at this quote in a new tab)

Potential budget impact: uptake convention in the ICER reference case

“Assume an equal proportion of patients (20%) are treated each year over five years, arriving at cumulative 100% at five years.” (opens the source at this quote in a new tab)