Evicenter
P&T meetings

Zanzalintinib (XL092)

Metastatic colorectal cancer

Manufacturer
Exelixis
Regulatory submission
NDA submitted December 2025
Launch
Not announced
Last updated
65 sources

Economic information and modeling report

Modeling overview

1 evidence topic · 2 sources

Summary

The economic evidence in this report concerns the disease and comparator treatment pathways. A systematic review reported average metastatic colorectal cancer treatment costs ranging from $12,346 to $293,461 across heterogeneous studies. A separate analysis of 82 participants used a US Medicare payer perspective and reported an incremental cost-effectiveness ratio of US$518,000 per quality-adjusted life-year gained. These figures do not estimate the acquisition cost, cost effectiveness, or budget impact of zanzalintinib.

Zanzalintinib-specific health technology assessment

No evidence found.

Zanzalintinib-specific acquisition price, annual treatment cost, price corridor, cost-effectiveness analysis, and budget-impact results

No evidence found.

Public zanzalintinib-specific economic model

No evidence found.