Zeleciment rostudirsen (z-rostudirsen)

Name: Zeleciment rostudirsen (z-rostudirsen) in Duchenne muscular dystrophy: Pathophysiology
Published: 2026-09-14T15:39:06-04:00

Duchenne muscular dystrophy

Also known as DYNE-251

Manufacturer: Dyne Therapeutics
Regulatory submission: BLA submitted May 2026
Launch: Anticipated in the first quarter of 2027
Last updated: September 19, 2026

Section

Product information and disease description Place of product in therapy Disease description

Pathophysiology

1 evidence topic · 2 sources

Pathophysiology

“Without a working DMD gene, the body can’t make enough working dystrophin protein.” (opens the source at this quote in a new tab)
“Without dystrophin, muscles can’t repair themselves properly.” (opens the source at this quote in a new tab)
“This eventually causes muscle weakness.” (opens the source at this quote in a new tab)