Evicenter
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Bezuclastinib

Nonadvanced systemic mastocytosis

Manufacturer
Cogent Biosciences
Regulatory submission
NDA submitted December 2025
Last updated
62 sources

Product information and disease descriptionPlace of product in therapyDisease description

Clinical presentation - signs and symptoms

4 evidence topics · 1 source

Dermatological symptoms: MS2D2 domains

“Itching; Flushing; Skin redness; Covered with spots.” (opens the source at this quote in a new tab)

Gastrointestinal and pain symptoms: MS2D2 domains

“Nausea; Abdominal pain; Bone pain; Headache.” (opens the source at this quote in a new tab)

Neurocognitive symptoms: MS2D2 domains

“Difficulty concentrating; Difficulty remembering things.” (opens the source at this quote in a new tab)

Fatigue symptoms: MS2D2 domains

“Feeling of tiredness.” (opens the source at this quote in a new tab)