Evicenter
P&T meetings

Molgramostim Inhalation Solution

Autoimmune pulmonary alveolar proteinosis

Manufacturer
Savara
Regulatory submission
BLA resubmitted December 2025
Launch
Not announced
Last updated
89 sources

Product information and disease descriptionProduct descriptionProduct informationPharmacology

Mechanism of action

2 evidence topics · 2 sources

Proposed restoration of alveolar macrophage function

“We believe that inhalation of MOLBREEVI activates macrophages in the lung alveoli, thus potentially restoring the surfactant-clearing activity of the alveolar macrophages” (opens the source at this quote in a new tab)

GM-CSF regulation of surfactant homeostasis and host defense

“In the lungs, GM-CSF regulates surfactant homeostasis and lung host defense through innate immune function.” (opens the source at this quote in a new tab)