Section 1 of 6
Terms and abbreviations
1 evidence topic · 0 sources
| Abbreviation | Term |
|---|---|
| AHFS | American Hospital Formulary Service |
| Ala | Alanine |
| ATP | Adenosine triphosphate |
| AU$ | Australian dollars |
| AUD | Australian dollars |
| CAD$ | Canadian dollars |
| CI | Confidence interval |
| CLIA | Clinical Laboratory Improvement Amendments |
| CRL | Complete response letter |
| DCA | Dichloroacetate |
| DLD | Dihydrolipoamide dehydrogenase |
| eIND | Emergency investigational new drug |
| FDA | Food and Drug Administration |
| Glut1DS | Glucose transporter type 1 deficiency syndrome |
| GSTZ1 | Glutathione transferase zeta 1 |
| ITT | Intention-to-treat |
| IV | Intravenous |
| KDTs | Ketogenic diet therapies |
| Leu | Leucine |
| Lys | Lysine |
| MAAI | Maleylacetoacetate isomerase |
| MELAS | Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes |
| NDA | New drug application |
| ObsRO | Observer-reported outcome |
| PDC | Pyruvate dehydrogenase complex |
| PDCD | Pyruvate dehydrogenase complex deficiency |
| PDH | Pyruvate dehydrogenase |
| PDHA1 | Pyruvate dehydrogenase E1 subunit alpha 1 |
| PDHD | Pyruvate dehydrogenase deficiency |
| PDK | Pyruvate dehydrogenase kinase |
| PDUFA | Prescription Drug User Fee Act |
| PK | Pharmacokinetics |
| PMPM | Per member per month |
| QT | QT interval on the electrocardiogram |
| QTc | Heart-rate-corrected QT interval |
| RMB | Renminbi |
| RNAi | RNA interference |
| SL1009 | Development code for sodium dichloroacetate |
| SN | Sensitivity |
| SP | Specificity |
| UMDF | United Mitochondrial Disease Foundation |
| US$ | United States dollars |
| w/o | Washout |