Evicenter
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Tirabrutinib

Primary central nervous system lymphoma

Regulatory submission
NDA submitted December 2025
Last updated
72 sources

Clinical evidence

Vitreoretinal lymphoma with spinal-cord involvement

3 evidence topics · 1 source

Objective
Location and study date

No evidence found.

Study design
Eligibility criteria

Not applicable.

Treatment
Study outcomes
Rationale for using clinical response as an observed outcome

Not applicable.

Statistical analysis description
Number of participants (Planned and analyzed)
Description of analysis sets

Not applicable.

Results
Participant disposition

No evidence found.

Baseline characteristics
Efficacy results
Health-related quality of life and patient-reported outcomes

No evidence found.

Safety results

No evidence found.

Study limitations
Summary

The retained case describes a temporary response in a participant with refractory vitreoretinal lymphoma and spinal-cord recurrence after chemotherapy and whole-brain radiotherapy. It does not provide a generalizable estimate of response duration or comparative efficacy.