Wholesale acquisition cost at U.S. introduction: manufacturer filing with the California Department of Health Care Access and Information

Field	Quoted record
Manufacturer name	“Intrabio Inc.”
National drug code	“83853010101”
Drug product description	“Aqneursa (levacetylleucine) 1 gram sachet, carton of 28”
Date introduced to market	“2024-09-24”
Wholesale acquisition cost at introduction (USD)	“13450.0000”

Cost per packet and cost at the maximum labeled dose: Oklahoma Medicaid review, February 2025

Product	Cost per unit	Cost per 30 days	Cost per year
Aqneursa (levacetylleucine) 1 g packet	“$480.36”	“$57,643.20”	“$691,718.40”

“Cost per 30 days based on the FDA approved max dose of 4g per day.” (opens the source at this quote in a new tab)
“Unit = each capsule or packet” (opens the source at this quote in a new tab)
“Costs do not reflect rebated prices or net costs. Costs based on National Average Drug Acquisition Costs (NADAC), Wholesale Acquisition Costs (WAC), or State Maximum Allowable Costs (SMAC).” (opens the source at this quote in a new tab)

Estimated wholesale acquisition cost per 28 days: pharmacy benefit manager summary, fourth quarter 2024

Product	Estimated wholesale acquisition cost (WAC)
Aqneursa (levacetylleucine)	“$40K per 28 days”

Company price disclosure at the 2024 launch

“IntraBio has not released the cost of its medication and did not answer questions about pricing but said it has an access program that will help cover the cost of the medication while working with insurance to pay for it.” (opens the source at this quote in a new tab)

Federal Supply Schedule and Big Four prices per carton of 28 packets

Price type	Quoted trade name	Quoted package	Quoted price (USD)	Quoted price start date	Quoted price stop date
Federal Supply Schedule	“AQNEURSA 1GM/PKT GRANULES”	“28”	“13339.54”	“01/01/2026”	“06/30/2030”
Big Four	“AQNEURSA 1GM/PKT GRANULES”	“28”	“10206.02”	“01/01/2026”	“06/30/2030”

New York Medicaid maximum reimbursable amount per packet: list effective 29 September 2026

Field	Quoted record
Description	“AQNEURSA 1 GRAM GRANULE PACKET”
National drug code	“83853-0101-01”
Maximum reimbursable amount cost	“555.7142800”
Basis of maximum reimbursable amount	“EA”
Effective date	“09/29/2026”
Maximum quantity	“112.000”

“Displays the maximum total reimbursement per drug unit.” (opens the source at this quote in a new tab)

Reported cost at the time of the ataxia-telangiectasia approval: Fierce Pharma, September 2026

“The drugmaker manages a financial support program to help families offset the out-of-pocket costs of Agneursa, which can cost $15,000 every one to two weeks.” (opens the source at this quote in a new tab)

Pharmacy cash price per carton of 28 packets

“The cost for Aqneursa 1 g oral granule for reconstitution is around $15,207 for a supply of 28 granule for reconstitution, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans.” (opens the source at this quote in a new tab)

Wholesale acquisition cost announced with the ataxia-telangiectasia approval

No evidence found.

Annual cost by body weight band

No evidence found.

National Average Drug Acquisition Cost

No evidence found.

Average sales price

Not applicable.