Product information and disease description Place of product in therapy Disease description Burden of Ataxia-telangiectasia

Economic burden and healthcare resource utilization

3 evidence topics · 3 sources

Cost-of-illness and claims-based studies specific to ataxia-telangiectasia

No evidence found.

Cost of illness of inherited ataxia in Ireland: a cohort that included 4 participants with ataxia-telangiectasia

“One hundred twenty-nine respondents completed a cross-sectional study on healthcare resource utilisation for progressive ataxia in Ireland. Costs were calculated using a prevalence-based approach and bottom-up methodology.” (opens the source at this quote in a new tab)
“Of the remaining 129, 56 (43%) had FRDA and 18 (14%) had a different type of inherited ataxia (Non-FRDA): these included ataxia-telangiectasia (n = 4)” (opens the source at this quote in a new tab)
“The COI for inherited ataxia in 2016 was €59,993 per person per year. Results were similar between participants with Friedreich’s ataxia (FRDA, n = 56), non-FRDA (n = 18) and those with undetermined ataxia (n = 55).” (opens the source at this quote in a new tab)
“Indirect costs, based on productivity losses by participants or caregivers, accounted for 52% of the cost of illness.” (opens the source at this quote in a new tab)
“Over two thirds of participants required professional or informal homecare and used a wheelchair.” (opens the source at this quote in a new tab)

Intensive care admissions at one academic center, 1995 to 2009

“Seven consecutive patients with confirmed diagnosis of ataxia-telangiectasia had nine intensive care admissions between January 1995 and December 2009.” (opens the source at this quote in a new tab)
“Mean duration of intensive care unit stay was 17 days (median, 9 days; range, 2-39 days). The most common admitting diagnosis was respiratory distress (six of seven patients).” (opens the source at this quote in a new tab)
“Forty-three percent (three of seven patients) survived to intensive care unit discharge with a 3-yr survival that was 14% (one of seven patients).” (opens the source at this quote in a new tab)

Hospital visits and admissions as a disruption to schooling

“Repeated hospital visits or admissions and the resultant disruption to schooling and the child's social life could also be important factors that contribute to the unexplained variance in parental QoL scores.” (opens the source at this quote in a new tab)