Name: Azetukalner (XEN1101) in Focal onset seizures: Ketogenic dietary therapy
Published: 2026-09-21T21:41:53-04:00

Product information and disease description Place of product in therapy Approaches to treatment Current treatment options and standard of care

Ketogenic dietary therapy

3 evidence topics · 3 sources

Ketogenic diet in drug-resistant epilepsy

“Consider a ketogenic diet under the guidance of a tertiary epilepsy specialist, in people with:” (opens the source at this quote in a new tab)
“drug-resistant epilepsy if other treatment options have been unsuccessful or are not appropriate.” (opens the source at this quote in a new tab)

Ketogenic diet in adults with intractable epilepsy: meta-analysis

“We identified 402 articles, of which, 16 studies including 338 patients met the inclusion criteria.” (opens the source at this quote in a new tab)
“The results of the meta-analysis showed that the combined efficacy rates of all the symptoms of seizure freedom, seizure reduction by 50% or more, and seizure reduction below 50% in adults with intractable epilepsy were 13%, 53%, and 27%, respectively.” (opens the source at this quote in a new tab)

Recommendations for ketogenic dietary therapy in adults

“Surveys were obtained from 20 medical institutions with >2,000 adult patients treated with KDTs for epilepsy or other neurologic disorders.” (opens the source at this quote in a new tab)
“KDTs may be safe and effective in treating adults with drug-resistant epilepsy, and there is emerging evidence supporting the use in other adult neurologic disorders and general medical conditions as well.” (opens the source at this quote in a new tab)