Name: BIM-IOL System in Open-angle glaucoma or ocular hypertension: Clinical presentation - signs and symptoms
Published: 2026-09-17T18:17:42-04:00

Product information and disease description Place of product in therapy Disease description

Clinical presentation - signs and symptoms

6 evidence topics · 7 sources

Early disease: absence of symptoms

“At first, glaucoma doesn’t usually have any symptoms. That’s why half of people with glaucoma don’t even know they have it.” (opens the source at this quote in a new tab)
“Over time, you may slowly lose vision, usually starting with your side (peripheral) vision” (opens the source at this quote in a new tab)

“Chronic forms of glaucoma are painless and symptomatic visual-field defects occur late.” (opens the source at this quote in a new tab)

Visual symptoms: peripheral vision loss and associated complaints

“Symptoms more common among glaucoma patients compared with glaucoma suspects included better vision in 1 eye, blurry vision, glare, sensitivity to light, cloudy vision, missing patches of vision, and little peripheral vision. Worse severity ratings for the symptom "little peripheral vision" explained the most variance in VF damage (43%).” (opens the source at this quote in a new tab)

Visual symptoms: distinguishing glaucoma from cataract

“Compared with cataract patients, glaucoma patients were more likely to report poor peripheral vision (OR 7.24, 95% CI: 2.53-20.72) and missing patches (OR 4.91, 95% CI: 1.52-15.84), but less likely to report worsening vision (OR 0.08, 95% CI 0.03-0.22), explaining 33% of the variance in diagnosis (ie, glaucoma vs. cataract).” (opens the source at this quote in a new tab)
“Asking about visual symptoms may serve as a useful diagnostic adjunct and inform decision-making, for example, in glaucoma patients considering cataract surgery.” (opens the source at this quote in a new tab)

Functional symptoms: late-stage vision loss and daily activities

“Glaucoma progresses without causing symptoms until the disease is advanced with substantial amounts of neural damage. When symptoms do occur, the disease results in vision loss with concomitant reduction in quality of life and the ability to perform daily activities, such as driving.” (opens the source at this quote in a new tab)

Signs: optic nerve and retinal nerve fiber layer findings

“Diffuse or focal narrowing, or notching, of the optic disc rim, especially at the inferior or superior poles” (opens the source at this quote in a new tab)
“Progressive narrowing of the neuroretinal rim with an associated increase in cupping of the optic disc” (opens the source at this quote in a new tab)
“Diffuse or localized thinning of the parapapillary RNFL, especially at the inferior or superior poles.” (opens the source at this quote in a new tab)

Psychological symptoms: depression

“Thirty-eight studies including 21,705 patients with glaucoma contributed to the single-group prevalence meta-analysis; pooled depression prevalence was 26.03% (95% CI, 21.10%-31.64%; prediction interval 5.98%-66.04%).” (opens the source at this quote in a new tab)
“GRADE certainty was very low for the comparative, prevalence, and longitudinal evidence domains.” (opens the source at this quote in a new tab)