Name: BIM-IOL System in Open-angle glaucoma or ocular hypertension: Long-term morbidity
Published: 2026-09-17T18:17:42-04:00

Product information and disease description Place of product in therapy Disease description

Long-term morbidity

6 evidence topics · 6 sources

Falls and fractures: population-based cohort in England

“Compared with comparators, there was an increased risk of falls in those with cataract (adjusted hazard ratio [HR], 1.36; 95% CI, 1.35-1.38), AMD (HR, 1.25; 95% CI, 1.23-1.27), and glaucoma (HR, 1.38; 95% CI, 1.35-1.41). Likewise for fractures, there were increased risks in all eye diseases, with an HR of 1.28 (95% CI, 1.27-1.30) in the cataract cohort, an HR of 1.18 (95% CI, 1.15-1.21) for AMD, and an HR of 1.31 (95% CI, 1.27-1.35) for glaucoma.” (opens the source at this quote in a new tab)

Falls by glaucoma severity: United States clinic cohort

“Of the glaucoma participants, 36% reported at least one fall in the prior 12 months compared to 20% of controls (adjusted odds ratio [OR], 2.7; 95% CI, 1.18–6.17; p=0.018). Compared to controls, the mild glaucoma group trended towards a higher fall risk (adjusted OR, 2.43; 95% CI, 0.97–6.08; p=0.059) and the advanced group had the highest fall risk (adjusted OR, 7.97; 95% CI, 2.44–26.07; p=0.001).” (opens the source at this quote in a new tab)

Falls or fractures by severity: United States claims analysis

“Severe OAG patients had significantly higher odds of fall or fracture compared with OHT patients (odds ratio, 1.34; 95% confidence interval, 1.13-1.59).” (opens the source at this quote in a new tab)

Driving: motor vehicle collisions

“over six times more likely to have been involved in one or more MVCs in the previous 5 years (OR(adjusted) = 6.62; 95% CI, 1.40-31.23), and more likely to have been at fault (OR(adjusted) = 12.44; 95% CI, 1.08-143.99).” (opens the source at this quote in a new tab)

Visual disability and activities of daily living

“Patients with glaucoma may struggle with daily activities such as reading, walking, and driving.” (opens the source at this quote in a new tab)
“Performance on these activities deteriorates with worsening of glaucoma severity or when both eyes are affected.” (opens the source at this quote in a new tab)
“Patients with glaucoma are more likely to experience falls and more likely to be involved in motor vehicle collisions compared with people without glaucoma.” (opens the source at this quote in a new tab)

Vision-affecting glaucoma in the United States

“An estimated 1.49 million people (UI, 1.17 million to 1.90 million) were living with vision-affecting glaucoma, with a prevalence of 0.57% (UI, 0.45%-0.73%) among people 18 years or older and 0.91% (UI, 0.71%-1.16%) among people 40 years or older.” (opens the source at this quote in a new tab)