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Duravyu (vorolanib intravitreal insert)

Wet age-related macular degeneration

Also known as EYP-1901
Manufacturer
EyePoint
Launch
Not announced
Last updated
136 sources

Product information and disease descriptionPlace of product in therapyDisease descriptionBurden of Wet age-related macular degeneration

Economic impact of diagnostic testing

5 evidence topics · 2 sources

Summary: economic impact of diagnostic testing

Diagnosis and retreatment decisions rely on retinal imaging, principally OCT (CPT 92134), with fluorescein angiography when indicated. In a US Medicare analysis covering 2008 to 2015, reimbursement for OCT imaging used to guide anti-VEGF therapy for neovascular AMD totaled an estimated $0.8 billion, while OCT-guided personalized dosing was estimated to have saved Medicare $10.3 billion in anti-VEGF drug and injection costs, for a net government saving of $9.0 billion. The estimated annual beneficiary copayment for OCT imaging was $6, compared with $242 for aflibercept on a personalized injection schedule. No current Medicare fee schedule amount for OCT or fluorescein angiography was retrieved from a primary CMS source.

Beneficiary copayment for OCT imaging
Cost componentRanibizumabBevacizumabAflibercept
Drug copay cost, personalized-injection schedule“$288”“$9”“$242”
OCT imaging copay cost, personalized-injection schedule“$6”“$6”“$6”
Injection copay cost, personalized-injection schedule“$20”“$20”“$20”
Optical coherence tomography visits over 12 months by baseline disease status
Optical coherence tomography test-related visits over 12 monthsAll prevalent nAMD (N = 6,076)Active CNV (N = 3,653)Inactive CNV (N = 1,046)Inactive scar (N = 358)
Patients with at least 1 visit, n (%)“5,350 (88.1)”“3,384 (92.6)”“893 (85.4)”“253 (70.7)”
Number of unique visits, mean (SD)“4.5 (3.5)”“5.4 (3.6)”“2.9 (2.6)”“1.6 (1.9)”