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Emcitate (tiratricol)

MCT8 deficiency

Last updated
78 sources

Product information and disease descriptionProduct descriptionProduct information

Generic, brand name and therapeutic class of product

5 evidence topics · 7 sources

Generic name
FieldQuoted record
Name of medicine“Emcitate”
Active substance“tiratricol”
International non-proprietary name (INN) or common name“tiratricol”
Brand name

“Tiratricol (Emcitate®) is an orally bioavailable small molecule being developed by Egetis Therapeutics for the treatment of monocarboxylate transporter 8 (MCT8) deficiency.” (opens the source at this quote in a new tab)

“EMCITATE® is a registered trademark of Rare Thyroid Therapeutics International AB” (opens the prescribing information at this quote)

Manufacturer: Egetis Therapeutics

“The approval of Emcitate was granted to Egetis Therapeutics US Inc.” (opens the source at this quote in a new tab)

“Manufactured for: Rare Thyroid Therapeutics International AB” (opens the prescribing information at this quote)

“Distributed by Egetis Therapeutics US Inc., Cambridge, MA 02142, USA.” (opens the prescribing information at this quote)

“Rare Thyroid Therapeutics International is a wholly owned subsidiary of Egetis Therapeutics” (opens the source at this quote in a new tab)

Therapeutic class: thyroid hormone receptor agonist

“EMCITATE tablets for oral suspension contain tiratricol, a thyroid hormone receptor agonist.” (opens the prescribing information at this quote)

“The active substance of Emcitate is tiratricol, an analogue of the thyroid hormone T3, the most important active thyroid hormone.” (opens the source at this quote in a new tab)

Chemical description

“The chemical name for tiratricol is 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid.” (opens the prescribing information at this quote)

“The molecular formula of tiratricol is C14H9I3O4, its molecular weight is 621.93 g/mol and its chemical structure is depicted below.” (opens the prescribing information at this quote)

“Tiratricol is a white to off-white solid powder, with a pH-dependent solubility in water.” (opens the prescribing information at this quote)