Evicenter
P&T meetings

Imsidolimab

Generalized pustular psoriasis

Regulatory submission
BLA submitted December 2025
Last updated
85 sources

Product information and disease descriptionPlace of product in therapyDisease descriptionBurden of Generalized pustular psoriasis

Economic burden and healthcare resource utilization

6 evidence topics · 8 sources

United States case series

“In the initial encounter, 35 patients (36.8%) were hospitalized and 64 (67.4%) were treated with systemic therapies.” (opens the source at this quote in a new tab)

Economic burden systematic review

“ten eligible studies” (opens the source at this quote in a new tab)

“across five countries” (opens the source at this quote in a new tab)

“the leading cost drivers for GPP were the costs of inpatient admissions and medications.” (opens the source at this quote in a new tab)

United States economic burden

“GPP patients experienced significantly higher total healthcare costs compared to matched cohorts (GPP vs plaque psoriasis: cost ratio 1.36, 95% confidence interval (1.22, 1.50); GPP vs control: 5.58 (3.73, 8.36)).” (opens the source at this quote in a new tab)

“Rates of inpatient visits were 4 times higher in GPP patients and 2 times higher in PPP patients compared to their matched cohorts.” (opens the source at this quote in a new tab)

“GPP and PPP patients have significant economic burden due to higher direct medical and pharmacy costs.” (opens the source at this quote in a new tab)

United States healthcare utilization, flares, and severity

“GPP patients who flared and had more severe disease had greater HCRU and charges.” (opens the source at this quote in a new tab)

Finland economic burden

“Flares were also associated with 2.5-fold higher indirect costs (cost ratio 2.5; 95% CI, 1.6–4.0; p < 0.001) compared with no flares.” (opens the source at this quote in a new tab)

Taiwan national claims study

“Median monthly healthcare costs were approximately twice as high among patients with GPP as among matched patients with PV.” (opens the source at this quote in a new tab)