Evicenter
P&T meetings

Imsidolimab

Generalized pustular psoriasis

Regulatory submission
BLA submitted December 2025
Last updated
85 sources

Product information and disease descriptionPlace of product in therapyDisease descriptionBurden of Generalized pustular psoriasis

Humanistic burden and health-related quality of life

6 evidence topics · 7 sources

Health-related quality-of-life systematic review

“In total 44 records that reported on 20 studies met the eligibility criteria and were retained for data extraction.” (opens the source at this quote in a new tab)

France: patient-reported burden

“High scores for fatigue, stress, skin and joint pain were reported, with 65% of patients at risk of mild to severe depression.” (opens the source at this quote in a new tab)

Patient-reported burden

“Dermatology Life Quality Index scores indicated a moderate to extremely large impact on QoL in nine patients (50%).” (opens the source at this quote in a new tab)

Sweden health-related quality of life

“The HRQoL was significantly worse in individuals with GPP compared to individuals with plaque psoriasis.” (opens the source at this quote in a new tab)

Malaysia health-related quality of life

“DLQI and EQ-5D for the patients with GPP were 8.44 (SD: 7.12) and 0.74 (SD: 0.27), respectively.” (opens the source at this quote in a new tab)

Real-world evidence review

“The impact of GPP on patients’ daily activities was significant, even in the absence of a flare.” (opens the source at this quote in a new tab)