Evicenter
P&T meetings

SL1009 (sodium dichloroacetate)

Pyruvate dehydrogenase complex deficiency

Manufacturer
Saol Therapeutics
Regulatory submission
NDA resubmitted June 2026
Launch
Not announced
Last updated
78 sources

Product information and disease descriptionPlace of product in therapyDisease description

Diagnosis

3 evidence topics · 4 sources

Molecular genetic testing

“molecular genetic testing for a mutation that causes PDCD” (opens the source at this quote in a new tab)

Previously unrecognized disease in female carriers

“We identified seven female PDHA1 carriers from five families.” (opens the source at this quote in a new tab)

“Five of them exhibited clinical features of the disease and were previously undiagnosed” (opens the source at this quote in a new tab)

Investigational amino-acid screening ratios

“Ala/Lys ≥3.0 and Ala/Leu ≥5.0” (opens the source at this quote in a new tab)

“identified patients with PDCD with 100% SN and ~85% SP.” (opens the source at this quote in a new tab)