Evicenter
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Anaphylm

Type I allergic reactions including anaphylaxis

Also known as dibutepinephrine, AQST-109
Regulatory submission
NDA resubmitted September 2026
Launch
Not announced
121 sources

Section 1 of 6

Terms and abbreviations

1 evidence topic · 0 sources

AbbreviationTerm
AAAAIAmerican Academy of Allergy, Asthma and Immunology
AARAcute allergic reaction
ACEAngiotensin-converting enzyme
AEAdverse event
AHFSAmerican Hospital Formulary Service
APCAntigen-presenting cell
ATCAnatomical Therapeutic Chemical
AUCArea under the concentration-time curve
CEACost-effectiveness analysis
CFRCase fatality rate
CIConfidence interval
CMCChemistry, manufacturing, and controls
COMTCatechol-O-methyltransferase
CRLComplete Response Letter
CVCardiovascular
CVDCardiovascular disease
DBPDiastolic blood pressure
DDDDefined daily dose
DESFDibutepinephrine sublingual film
EAIEpinephrine auto-injector
EDEmergency department
EMAEuropean Medicines Agency
EMSEmergency medical services
EOP2End of phase 2
FAFood allergy
FAANFood Allergy and Anaphylaxis Network
FAIMFood Allergy Independent Measure
FDAFood and Drug Administration
GA2LENGlobal Allergy and Asthma European Network
GIGastrointestinal
HCPHealth care professional
HFHuman factors
HRQoLHealth-related quality of life
ICERIncremental cost-effectiveness ratio
IgEImmunoglobulin E
IgGImmunoglobulin G
IMIntramuscular
INDInvestigational new drug
IQRInterquartile range
IVIntravenous
MCDDMultiple cause of death data
MRGPRX2Mas-related G protein-coupled receptor X2
NADACNational Average Drug Acquisition Cost
NDANew drug application
NEDSNationwide Emergency Department Sample
NIAIDNational Institute of Allergy and Infectious Diseases
NISNational Inpatient Sample
NMBNet monetary benefit
NSAIDNonsteroidal anti-inflammatory drug
OACOral allergen challenge
OASOral allergy syndrome
OFCOral food challenge
OHCAOut-of-hospital cardiac arrest
OITOral immunotherapy
PAFPlatelet-activating factor
PDPharmacodynamics
PDUFAPrescription Drug User Fee Act
PFASPollen-food allergy syndrome
PKPharmacokinetics
PMHPast medical history
QALDQuality-adjusted life-day
QALYQuality-adjusted life-year
RDRepeat dose
SADSingle ascending dose
SAESerious adverse event
SBPSystolic blood pressure
SCSubcutaneous
SDStandard deviation
SLSublingual
SPTSkin prick test
TEAETreatment-emergent adverse event
TNFTumor necrosis factor
TRxTotal prescriptions
WAOWorld Allergy Organization
WHOWorld Health Organization