Cytisinicline

Name: Cytisinicline in Smoking cessation: Nicotinic acetylcholine receptor partial agonists
Published: 2026-09-14T15:39:06-04:00

Smoking cessation

Manufacturer: Achieve Life Sciences
Regulatory submission: NDA resubmission planned for the fourth quarter of 2026
Launch: Anticipated after potential approval in the first half of 2027
Last updated: September 19, 2026

Section

Product information and disease description Place of product in therapy Approaches to treatment Current treatment options and standard of care

Nicotinic acetylcholine receptor partial agonists

2 evidence topics · 3 sources

WHO tobacco cessation treatment guideline

“WHO recommends varenicline, Nicotine Replacement Therapy (NRT), bupropion, and cytisine as effective treatments for tobacco cessation.” (opens the source at this quote in a new tab)

WHO Essential Medicines List

“the Expert Committee recommended the addition of cytisine to the core list of the EML as a treatment option for tobacco and smoking cessation.” (opens the source at this quote in a new tab)