Name: Juvmo (tavapadon) in Parkinson's disease: Incidence of Parkinson's disease
Published: 2026-09-27T21:44:59-04:00

Product information and disease description Place of product in therapy Disease description Epidemiology

Incidence of Parkinson's disease

6 evidence topics · 1 source

Incidence in North America among adults aged 45 and 65 years and older

“The cohorts contained data on 6.7 million person-years of adults ages 45 and older, and 9.3 million person-years of adults ages 65 and older.” (opens the source at this quote in a new tab)
“Our estimates of age-sex-adjusted incidence of PD ranged from 108 to 212 per 100,000 among persons ages 65 and older, and from 47 to 77 per 100,00 among persons ages 45 and older.” (opens the source at this quote in a new tab)
“PD incidence increased with age and was higher among males.” (opens the source at this quote in a new tab)

Estimated number of new diagnoses per year in North America

“We established a range of total incident PD diagnoses in North America of approximately 60,000 to 95,000 among adults ages 45 and older.” (opens the source at this quote in a new tab)
“Using the Medicare administrative database alone for this same time period suggests an incident rate of PD of nearly 90,000 per annum just for those 65 and older.” (opens the source at this quote in a new tab)
“Nevertheless, this contrasts sharply with the estimate of 40,000-60,000 new cases per annum that has been cited previously for PD incidence” (opens the source at this quote in a new tab)

Incidence by sex among adults aged 65 years and older

“Age standardized PD incidence estimates for ages 65 and older ranged from 108 to 212 per 100, 000 person-years, from 162 to 277 among males, and from 66 to 161 among females.” (opens the source at this quote in a new tab)
“As shown in Fig. 1, incidence estimates were higher in males as compared to females at all ages in the datasets which allowed sex-based comparisons into the 8th decade” (opens the source at this quote in a new tab)

Incidence by age

“As examined in persons aged 65 and older, PD incidence estimates increased with age in the decades 65–74 years, 75–84 years in every study sample.” (opens the source at this quote in a new tab)
“PD incidence among males rose first, most sharply between ages 64 and 74 in the fourstudy cohorts.” (opens the source at this quote in a new tab)

Variation in incidence by case ascertainment method

“The Ontario Health care and Medicare program datasets produced incidence rates that were 1.5–2.0 times higher than found in among Kaiser Permanente Northern California members or the HAAS and Rochester Epidemiology Project cohorts.” (opens the source at this quote in a new tab)
“The HAAS, REP, and KPNC studies, which produced lower incidence estimates, required high levels of clinical evidence and diagnosis by an expert clinician (a neurologist or movement disorders neurologist), even after screening, similar to the diagnostic protocols used for entry into a PD research study or clinical trial.” (opens the source at this quote in a new tab)

Geographic variation in incidence among Medicare beneficiaries

“A clustering of counties with a higher incidence of PD was observed at the juxtaposition of the Midwestern and Southern regions of the United States.” (opens the source at this quote in a new tab)
“Lower incidence areas included the Mountain West region, the western Midwest, and the far Northwest.” (opens the source at this quote in a new tab)