Evicenter
P&T meetings

SL1009 (sodium dichloroacetate)

Pyruvate dehydrogenase complex deficiency

Manufacturer
Saol Therapeutics
Regulatory submission
NDA resubmitted June 2026
Launch
Not announced
Last updated
78 sources

Product information and disease descriptionPlace of product in therapyDisease descriptionBurden of Pyruvate dehydrogenase complex deficiency

Humanistic burden and health-related quality of life

3 evidence topics · 3 sources

Patient-reported disease burden

“More than 84% of survey respondents cited muscle weakness as one of the three most impactful symptoms” (opens the source at this quote in a new tab)

Caregiver burden: broader mitochondrial disease

“often resulting in poor functional and survival outcomes for the patient and considerable psychosocial distress for the caregiver.” (opens the source at this quote in a new tab)

Broader mitochondrial disease review: utility evidence

“No studies reported utilities data.” (opens the source at this quote in a new tab)