Product information and disease description Place of product in therapy Disease description Epidemiology

Prevalence of Type I allergic reactions including anaphylaxis

9 evidence topics · 9 sources

Lifetime prevalence of anaphylaxis in the United States

“In the US, the lifetime prevalence of anaphylaxis is approximately 5% and appears to be rising.” (opens the source at this quote in a new tab)

Prevalence of food allergy, epinephrine prescription, and emergency department use among United States adults

“Estimated convincing food allergy prevalence among US adults was 10.8% (95% CI, 10.4%-11.1%), although 19.0% (95% CI, 18.5%-19.5%) of adults self-reported a food allergy.” (opens the source at this quote in a new tab)
“The most common allergies were shellfish (2.9%; 95% CI, 2.7%-3.1%), milk (1.9%; 95% CI, 1.8%-2.1%), peanut (1.8%; 95% CI, 1.7%-1.9%), tree nut (1.2%; 95% CI, 1.1%-1.3%), and fin fish (0.9%; 95% CI, 0.8%-1.0%).” (opens the source at this quote in a new tab)
“Regarding health care utilization, 24.0% (95% CI, 22.6%-25.4%) reported a current epinephrine prescription, and 38.3% (95% CI, 36.7%-40.0%) reported at least 1 food allergy–related lifetime emergency department visit.” (opens the source at this quote in a new tab)

Prevalence of food allergy and epinephrine autoinjector prescription among United States children

“Overall, estimated current FA prevalence was 7.6% (95% confidence interval: 7.1%–8.1%) after excluding 4% of children whose parent-reported FA reaction history was inconsistent with immunoglobulin E–mediated FA.” (opens the source at this quote in a new tab)
“The most prevalent allergens were peanut (2.2%), milk (1.9%), shellfish (1.3%), and tree nut (1.2%).” (opens the source at this quote in a new tab)
“Furthermore, 19.0% reported ≥1 FA-related emergency department visit in the previous year and 42.0% reported ≥1 lifetime FA-related emergency department visit, whereas 40.7% had a current epinephrine autoinjector prescription.” (opens the source at this quote in a new tab)

Distribution of food allergy across racial, ethnic, and income groups in the United States

“Food allergies affect approximately 8% of children and 11% of adults in the US.” (opens the source at this quote in a new tab)
“Non-Hispanic White individuals across all ages had the lowest rate of self-reported or parent-reported food allergies (9.5% [95% CI, 9.2%-9.9%]) compared with Asian (10.5% [95% CI, 9.1%-12.0%]), Hispanic (10.6% [95% CI, 9.7%-11.5%]), and non-Hispanic Black (10.6% [95% CI, 9.8%-11.5%]) individuals.” (opens the source at this quote in a new tab)
“Non-Hispanic Black individuals were most likely to report allergies to multiple foods (50.6% [95% CI, 46.1%-55.1%]).” (opens the source at this quote in a new tab)

Prevalence of allergy to multiple foods among United States children and adults

“Among children and adults meeting established symptom-report criteria for FA, an estimated 40% and 48% had multi-FA, respectively.” (opens the source at this quote in a new tab)

Pooled prevalence of food allergy and food sensitization in Europe

“Pooled lifetime and point prevalence of self‐reported FA were 19.9% (95% CI 16.6–23.3) and 13.1% (95% CI 11.3–14.8), respectively.” (opens the source at this quote in a new tab)
“The point prevalence of sensitization based on specific IgE (slgE) was 16.6% (95% CI 12.3–20.8), skin prick test (SPT) 5.7% (95% CI 3.9–7.4), and positive food challenge 0.8% (95% CI 0.5–0.9).” (opens the source at this quote in a new tab)

Prevalence of Hymenoptera venom anaphylaxis in a United States beneficiary population

“Fire ant and flying Hymenoptera-venom anaphylaxis prevalence in the general population was 0.048% and 0.083%, respectively. Fire ant-venom anaphylaxis prevalence in the 14 colonized states was 0.085%.” (opens the source at this quote in a new tab)

Prevalence of documented penicillin allergy in the United States

“In the US, 8 to 10% of the population and up to 15% of hospitalized patients have a documented penicillin allergy, limiting the use of these effective antibiotics.” (opens the source at this quote in a new tab)

Growth in adrenaline autoinjector prescriptions relative to hospital admissions

“Over the same time period, prescriptions for adrenaline autoinjectors increased by 336% (estimated rate ratio 1.113, 95% confidence interval 1.112 to 1.113; an increase of 11% per year).” (opens the source at this quote in a new tab)